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M., et al., Retatrutide, a GIP, GLP1 and Glucagon Receptor Agonist, for People With Type 2 Diabetes: A Randomised, DoubleBlind, Placebo and ActiveControlled, ParallelGroup, Phase 2 Trial Conducted in the USA, Lancet 402, no

Steroid dependence is something we see commonly in clinical practice and is associated with significant long-term side effects, so seeing a clear reduction was encouraging

That shift opens the door to practical problem-solving and helps preserve trust

Since CPP is a behavioral marker of a substances hedonic value, these results indicate that GLP-1RAs may attenuate the affective component of reinforcement, i.e., liking
This is especially important with the use of low-dose contraceptives that are dependent on threshold blood levels for birth control
