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Unlike some treatments where breaks prevent tolerance, stopping and restarting these medications typically results in weight regain during the break period followed by renewed side effects upon restart

Once-Weekly Convenience Single weekly injection significantly improves patient compliance compared to daily injectable therapies, making long-term adherence easier for patients

Baseline bleeding time and platelet counts may be warranted in high-risk populations to establish a safety profile

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In patients continuing GLP-1RA therapy, the use of point-of-care gastric ultra sound may be a reasonable strategy to enhance patient safety and prevent unnecessary surgical cancellations