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Figure 1 illustrates the diverse physiological effects of GLP-1RAs across major organ systems, including the pancreas, liver, brain, cardiovascular system, kidneys, gastrointestinal tract, and adipose tissue

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[119] conducted a phase II clinical trial in patients with NASH, that is, a placebo-controlled trial of subcutaneous sommarutide in the treatment of NASH, and found that sommarutide treatment resulted in a significantly higher proportion of patients in remission of NASH compared with placebo