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In a cross-sectional study presented at the European Association for the Study of Diabetes annual meeting and published in Diabetes, Obesity and Metabolism , researchers surveyed adults with obesity who were using semaglutide (Ozempic/Wegovy, Novo Nordisk) or tirzepatide (Mounjaro, Eli Lilly) and asked about changes in their appetite, satiety and sensory perception after starting an incretin-based therapy

Several RCTs including SAVORTIMI 53 (saxagliptin) [52], EXAMINE (alogliptin) [53], and TECOS (sitagliptin) [54] have shown that DPP4 inhibitors did not significantly reduce stroke risk [1]

PubMed, 2024 Glucagon-like peptide-1 receptor agonists and muscle strength changes in older adults British Journal of Pharmacology, 2025 Consuming more protein may protect patients taking an anti-obesity drug from muscle loss Endocrine Society, ENDO 2025 Preserving Lean Body Mass in Patients Taking GLP-1 for Weight Loss Mass General Advances in Motion GLP-1s and Lean Mass: What the Research Shows ACE Certified, June 2025 New GLP-1 Therapies Enhance Quality of Weight Loss by Improving Muscle Preservation American Diabetes Association, 2025 Impact of GLP-1 Receptor Agonist Therapy in Patients at High Risk for Sarcopenia Current Nutrition Reports, Springer, 2025