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Current Research Landscape : Investigational compounds, including retatrutide and tirzepatide, are undergoing active clinical trials as of 2026

Because they are less invasive, they often come with a lower price tag and require no downtime

"It's very tough to know why one patient's responding to something and another isn't," Traina said, adding that it's "one of the many benefits of having multiple treatment options available." Having an oral option at lower cash prices that "can be attainable for a larger population is a very good thing, to help us cure or alleviate this chronic disease state," said UCSD's Hofflich

Interestingly, both groups reported similar levels of adverse events and side effects

Like any active medication, Ozempic can cause adverse side effects as your digestive system adapts to slowed motility