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[DOI] [PMC free article] [PubMed] [Google Scholar] 104.Holz GG, Chepurny OG, Leech CA

It also affects the brain

On balance, the data and arguments presented above suggest some separation between those receptors accessible to gutderived hormonal GLP1 and brainderived neuromodulatory GLP1, but fail to deliver unequivocal proof

Other treatments like insulin [66] or metformin [67,68,69] have shown positive effects

Zepbound is unique because it acts on two gut hormones (GLP-1 and GIP), offering additional benefits
