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GLP-1 is a powerful hormone that controls hunger and blood sugar
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Semaglutide is known to cause constipation, but it often subsides within a few weeks
Furthermore, it had an anti-inflammatory impact via stimulating cyclic adenosine monophosphate (cAMP)/ protein kinase A (PKA)/ cAMP response element (CRE)-binding protein (CREB) signaling pathway and shifting M1/M2 macrophage polarization towards the M2
