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However, rodent studies have shown that long-term Glucagon-like Peptide-1 Receptor Agonists (GLP-1RAs) exposure can induce proliferative changes, including thyroid C-cell tumors and epithelial cell hyperplasia, through GLP-1Rmediated pathways, raising concerns about potential mitogenic effects in other tissues

Study outcomes included the number needed to treat (NNT) to prevent one case of clinical events, healthcare costs, and cost per case of event prevented

* El Acompaamiento Nutricional GLP-1 no es un medicamento y no ha sido evaluado clnicamente en pacientes que usan GLP-1

But over the next 12 months, the scale quietly crept upward

In obesity, GLP-1 RAs exert their effects by acting on the hypothalamus and GI system to reduce gastric emptying, enhance satiety and decrease appetite 11