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However, accumulating evidence has identified additional GI complications, including cholelithiasis, cholecystitis, gastroparesis, and bowel obstruction, which may warrant caution in susceptible individuals

Any study protocol should include regular monitoring of heart rate and other vital signs

Aim to drink regularly throughout the day, even if you're not craving water

The most frequent treatment-emergent adverse events were gastrointestinal symptoms, notably nausea, diarrhoea and constipation, which were typically mild-to-moderate and diminished over time
