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Clinical Evidence and Trial Data on GLP-1 and Menstrual Health Most large semaglutide trials (STEP 14) did not specifically measure menstrual changes as a primary endpoint, but real-world data from clinical practices shows the phenomenon is well-documented

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"[It] has really shown that stigma is still extremely prevalent and harmful, with people saying that people with obesity don't deserve healthcare," she said

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Many supplement protocols for tirzepatide users now include electrolytes as a standard recommendation, not just for dry mouth but for overall hydration support