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According to McKinsey, the market could reach between $120 billion and $280 billion by 2040 , representing a compound annual growth rate (CAGR) of 915% from 2022 levels
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Given the role of insulin, growth hormone, and sex steroids in pubertal maturation, pharmacological modulation of appetite and energy balance during this window may theoretically influence musculoskeletal development, bone mineralization, and long-term metabolic health

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GLP-1RAs increase natriuresis by inhibiting sodium reabsorption by acting on the Na/H exchanger in the proximal tubule of the kidney [75]
