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Non Alcoholic Fatty Liver Disease (NAFLD) consists of excessive lipid accumulation in the liver, lipotoxicity, inflammation, and potential progression to Non Alcoholic SteatoHepatitis (NASH), liver fibrosis, and hepatocellular carcinoma ( In this context, early improvement in body composition, assessed by segmental multifrequency bioelectrical impedance analysis (SMF-BIA) ( 2 Methods 2.1 Study design and institution This is a 26-weeks, open-label, real-life prospective study conducted at the Outpatient Section for Metabolic Disorders of the Department of Internal Medicine, University of Bari
By May 2025, the dosage had been systematically increased to a maintenance level of 2.4 mg weekly
Notably, GLP-1RA treatment increased the relative abundance of N, N-dimethyl sphingosine (DMS), an endogenous metabolite derived from sphingosine
Combining trazodone with NSAIDs (non-steroidal anti-inflammatory drugs) or blood thinners like warfarin can also increase the risk of bleeding
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