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Central to our findings is the role of the transcription factor YAP, whose disruption is crucial in the connection between obesity and TNBC chemoresistance

Today's episode is on the company behind these sensational Diabetes and weight loss drugs, Ozempic and Wegovy

These differing mechanisms of action explain why combining these medications theoretically might produce additive weight loss effects, but also why such combination therapy raises substantial safety concerns that have not been adequately studied in clinical trials

Your metabolism adapts: Studies on metabolic flexibility show that over time, your body becomes more efficient at switching between burning sugar and burning fat for energy

So the higher you get, the higher dose response, but it's it's diminishing returns