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declare that they have made a significant contribution to the work reported, whether in the conception, study design, execution, acquisition of data, data analysis and interpretation, or in all these areas

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On the other hand, GIP-green-fluoresent-protein (GFP)-knock-in (GIP gfp/+ ) mice, in which GIP secretion is attenuated to half that of WT mice, exhibit no decrease in bone mass compared to wild-type mice, with no significant difference in blood glucose or insulin levels during OGTT after 8 weeks of HFD, although slight glucose intolerance was observed under a normal diet [18, 100]

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The guidelines are expected to be published soon, following a public consultation held in September

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This growth has had ripple effects on common comorbid conditions associated with diabetes and obesity, including hypertension, high cholesterol, and gastroesophageal reflux disease (GERD)

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