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Central Pathways Associated with SGLT-2is Treatment Outcomes To date, only a handful of studies have reported the effects of SGLT-2is on the CNS, mainly due to complexity of SGLTs family, and a lack of research elucidating the exact roles of SGLT-2 in the CNS
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Particularly, this kinase can activate the Foxo transcription factors by phosphorylation (10)
