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The drug is marketed globally by Novo Nordisk as Ozempic for Type 2 diabetes and for obesity, and has been at the centre of a patent dispute in India.

These studies are conducted using controlled in vitro and in vivo models to better understand receptor activation, downstream signaling cascades, and peptide stability

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The highest dose wins on paper, but only by 1.4 percentage points over 10 mg, while gastrointestinal side effects keep rising and discontinuation creeps up