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The study enrolled a sufficient proportion of participants who required substantial weight loss84.0% of participants in this global registration trial had a baseline BMI 35 kg/m

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Conclusions Twenty-four weeks of acarbose monotherapy in newly diagnosed patients with T2D is associated with significantly increased levels of both fasting and postprandial GLP-1 as well as significantly increased NO levels and NOS activity for those patients in whom postprandial GLP-1 levels were increased