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Chronic ICV administration of oxyntomodulin, a GLP-1R agonist, in mice decreased body weight despite having no significant effects on food intake (Lockie et al., 2012)

The GLP-1 market, originally formulated for patients with Type 2 diabetes but now widely used for obesity, has undergone differing payer access across patient populations and payment channels

It is important to note that Ozempic is not used to treat type 1 diabetes, and is not the same as insulin

2022 doi: 10.2139/ssrn.4212371

Although many unforeseen corners could lie ahead, one thing is clear: Lilly and Novo revolutionized the weight-loss landscape through years of continual therapy improvements
