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PIONEER 3 and 4 offered post-hoc subgroup analyses for the primary and key secondary outcomes, change in A1C and change in body weight, by background therapy

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The weight loss journey with Retatrutide follows a predictable arc: adaptation and moderate loss during months 1-3, acceleration during months 4-6, continued progress with gradual slowing during months 7-9, and plateau/maintenance from month 10 onward

Leveraging nationwide primary care electronic health record data from the JAMDAS database, we investigated realworld practices in chronic kidney disease (CKD) management in Japan, with particular attention to laboratory testing and renal anemia care

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