obesity treatment with bariatric surgery vs glp-1 receptor agonists Outperforms GLP-1s in Weight Loss Obesity Treatment With Bariatric Surgery

In several RCTs, GLP-1 receptor agonists were compared with insulin or insulin-based intensification strategies, therapies that have been associated with hyperinsulinemia and potential pro-proliferative signaling

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Most of the subjects included in the available RCTs are PCOS patients with severe obesity, which do not reflect the entire clinical spectrum of PCOS encountered in clinical practice

In addition to not being a non-randomized controlled trial, criticisms of the study include that the published data was not sufficient to establish a causal association between GLP-1 receptor agonist use and NAION

By mimicking the bodys natural hormone, they help regulate blood sugar, curb appetite, and even protect heart health