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Study finds GLP-1 receptor agonists do not increase pancreatitis risk and are associated with fewer complications in Type 2 diabetes.

--- Here are some potential actions covered in the article for payers and employers to take as a result of this shift: Update formulary tiers and step therapy policies (consider the impact on comorbidities) Support members transitioning off GLP-1s after reaching their goals Create differentiated access pathways based on patient risk profiles Monitor realworld outcomes beyond A1C (cardiovascular, renal, adherence) Model the downstream impact on generics and legacy therapies --- Commercial plans are accelerating GLP-1 uptake and favoring the simplicity of a single therapy

An albumin engineering strategy (QMP) compensates for the poor PK properties resulting from cleavage, as demonstrated for a GLP-1 albumin fusion

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