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We addressed incoherence (inconsistency) both locally by comparing directly with indirect evidence using the Separating Indirect from Direct Evidence (SIDE) method [19] and globally using the design-by-treatment interaction model [20]

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This chemosensor, together with other 27 non-selective cationic channels, is part of a larger family named transient receptor potential (TRP) channel superfamily and is known to play an important role in the metabolic syndrome (361, 362)

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