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The gut microbiome itself is changing during GLP-1 treatment through multiple mechanisms, providing biological rationale for considering targeted gut-microbiome support as a parallel layer to the medication

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Clinical research shows semaglutide produces average weight loss of approximately 15% at 12 months, while tirzepatide demonstrates even more dramatic results with up to 20% average weight loss in the same timeframe

Other ways semaglutide can cause diarrhea include: Increased Fluid in the Intestines : Semaglutide affects how water is absorbed in the gut, leading to looser stools

Proper hygiene, including wiping front to back after using the bathroom, peeing after intercourse, and drinking plenty of fluids like water and cranberry juice are easy ways to prevent a UTI