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If additional trials confirm that they effectively curb cravings across addictive substances, these drugs could begin to close one of the most consequential treatment gaps in medicine

Given the multifactorial nature of obesity and the highly competitive, rapidly evolving AOM market, the factors that will determine which AOM is considered best-in-class are also likely to be complex

Another study reported that depression caused by chronic stress blocks glutamate signaling and synaptic transmission, and this ultimately leads to cognitive dysfunction (Yuen et al., 2012)

However, brand-name medications are currently available, and compounding is only allowed when the patient needs a customized dosage or formulation that is not commercially available

Some long-acting formulations that are typically injected once weekly include Semaglutide, Dulaglutide, EX-LAR (long-acting release formulation of Exenatide), and PEX-168 (polyethylene glycol Loxenatide) [2]