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Referral to specialists should be considered when patients have persistent A1C elevations despite combination therapy, complex obesity requiring specialized care, or when evaluating bariatric surgery options (typically for BMI 40 kg/m or 35 kg/m with comorbidities)

The nausea may be accompanied by decreased appetite, which may be excessive in some patients and require monitoring

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Alternate heat and cold depending on stiffness or inflammation

Consultation with a healthcare provider is crucial to assess potential risks and benefits based on the patient's medical history
