dpp4 and glp 1 together degrade the GLP1 incretion, which leads to suppression of the Insight into Structure Activity Relationship
Description
10.1001/jamanetworkopen.2024.6221 [DOI] [PMC free article] [PubMed] [Google Scholar] 31

Nausea is the most often reported GI side effect of GLP-1 medications

doi: 10.2337/diab.26.5.480

Clinical and observational research has shown that GLP-1 medications are associated with reduced alcohol cravings, lower consumption, and decreased risk of alcohol-related disorders GLP-1 use is already widespread in the U.S

polycystic ovarian syndrome, immigration 10 years prior, age over 95 years, eGFR below 30 mL/min/1.73 m 2 , heart failure, missing prebaseline HbA1c, HbA1c level below 42 mmol/mol, or gestational diabetes
