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Examples include the Food Standards Agency Nutrient Profiling System Dietary Index (FSA-NPS DI) (64), the Healthy Trolley Index (65) or the Grocery Purchase Quality Index-2016 (66)

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In the LEADER trial, over 9,340 patients with type 2 diabetes and high cardiovascular disease risk underwent randomization to liraglutide or placebo and were followed for a median of 3.8 years resulting in a 13% risk reduction in a combined endpoint of death from cardiovascular cause, nonfatal myocardial infarction, or nonfatal stroke [46]

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There's one area where berberine may actually have an advantage

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Brand-name FDA-approved name brand Ozempic, Mounjaro, Wegovy, Zepbound, Foundayo Regulation: FDA-approved and manufactured by Novo Nordisk or Eli Lilly

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