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230,231 GLP-1 RAs also have positive effects on endothelial function, including increasing nitric oxide production, allowing for increased blood flow, decreasing vascular stiffness, and providing nutrients that are delivered to a specific repair area

The most effective prebiotics for semaglutide users include partially hydrolyzed guar gum (PHGG), which improves stool consistency without excessive gas production, acacia fiber, which is gentle on sensitive stomachs and feeds Bifidobacterium species, and resistant starch from cooled potatoes, green bananas, or supplements, which selectively promotes butyrate-producing bacteria

doi: 10.3390/biomedicines9040383 [DOI] [PMC free article] [PubMed] [Google Scholar] 46

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