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These medications, which mimic the natural GLP-1 hormone, can help regulate appetite, increase feelings of fullness, and reduce calorie intake

Oral semaglutide (Rybelsus) is taken as a pill, while Ozempic and Wegovy are administered as an injection under the skin

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Some patients may experience minor, short-term side effects such as swelling, bruising, redness, discomfort, and numbness at the treatment side

A 2025 meta-analysis in JAMA Psychiatry found no increase in depression or suicidality with GLP-1 medications versus placeboin fact, some trials showed slightly lower depressive symptoms in the GLP-1 groups