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Satiety, clinical adiposity - liraglutide evidence in individuals w, without diabetes study g: Liraglutide and cardiovascular outcomes in adults with overweight or obesity: a post hoc analysis from SCALE randomized controlled trials

Tirzepatide is an increasingly popular injectable medication used to help overweight and obese individuals lose significant quantities of weight

People who experienced significant wearing-off on semaglutide often find the effect more noticeable after switching to tirzepatide, not because tirzepatide is less effective, but because its shorter half-life creates a wider gap between peak and trough levels

While both drugs have similar mechanisms of action, there are some key differences such as dosage, side effects and cost to consider before selecting one over the other