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95% CI [0.410.95]
In addition, it would mean that the entirety of Ex9s action is by impairing glucagon action on -cell GLP-1r since Ex9 had no impact on glucose tolerance in animals that had fully restored intestinal Gcg expression and postprandial circulating GLP-1 levels (27)
1) (the importance of bile in GIP secretion is discussed below)
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The apparent volume of distribution is 100 L, with approximately 55% of lixisenatide bound to plasma proteins in circulation (Table 3) [25]
