glp 1 masld Hepatokines and MASLD: The GLP1-Ras-FGF21-Fetuin-A Crosstalk as a Therapeutic Target Cardiovascular outcomes of GLP-1RA vs
Description
The study included 67,841 patients taking semaglutide (75.6%), 15,661 taking tirzepatide (17.5%), and 6,216 taking liraglutide (6.9%)

GLP-1 induces the expression of FNDC5 derivatives that execute lipolytic actions [dissertation]

More women reached clinically meaningful weight-loss thresholds, and cardiometabolic markers improved to a greater degree

The mechanisms by which GLP-1 receptor agonists induce natriuresis are unclear, but in both rodents and humans, GLP-1 receptor agonist infusion enhances kidney lithium clearance, a marker of proximal tubular sodium reabsorption, as well as urinary pH

GLP-1 wirkt nicht nur im Verdauungstrakt, sondern auch im zentralen Nervensystem - etwa im Hypothalamus, also dem Appetitzentrum des Gehirns
