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It's a little bit of a tragedy at commons where everyone throws their arms up and says, well, I'm going to go do the best I can and make sure I'm okay, because I I really don't know who to point to and be like, this system is effed up for this reason

It is expected to be widely available in the early 2030s, while the branded version still remains approved and available for treatment

Semaglutide, a long-acting GLP-1RA, has been approved for the treatment of T2DM and obesity by the Food and Drug Administration (FDA) (Ala and Moheb 2024)

Aside from the obvious difficulties in extrapolating a study of rats to humans, these studies all tend to be very small (its difficult and expensive to do a rat study, let alone one where you have to administer them an illegal drug)

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