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Currently, a double-blind, placebo-controlled randomized phase 3 study with aramchol at 300 mg in subjects with NASH and F2-3 who are overweight (or obese) and have prediabetes or adequately controlled T2DM (the ARMOR study) is underway (NCT04104321)

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They may also improve ovulation, menstrual cycle regularity, and pregnancy rates for people experiencing obesity or polycystic ovary syndrome

Endocrine cell changes, including -cell hyperplasia, glucagon-expressing microadenomas, and a sixfold increase in -cell mass, were also noted [17]