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Our meta-analysis integrating data from FinnGen, PGC, and UK Biobank cohorts enhanced statistical power by mitigating cohort-specific biases

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Interestingly, weight reduction is frequently associated with gallbladder and biliary tract disorders

A decline of 30% or more in eGFR was seen in 9.2% of patients on finerenone and 7.4% on placebo

Triple agonists including retatrutide show exceptional promise based on remarkable weight loss and liver fat normalization in early trials, with dedicated MASH histology studies ongoing