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In animal research, increasing plasma adiponectin levels through pharmacological or genetic means has shown to alleviate obesity-induced endothelial dysfunction, hypertension, atherosclerosis, myocardial infarction, and diabetic cardiomyopathy

They also affect the brain
People taking the oral form lost a significant percentage of their body weight , with results comparable to the injectable form in separate clinical studies

However, we were unable to present clear evidence concerning this speculation because of lack of data
