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Chronic inflammation increases the risk of organ damage and certain diseases and disorders in areas like the heart, brain, joints and gastrointestinal tract

In contrast to GLP-2 administration, subcutaneous injection of GLP-1 in healthy individuals had no effects on bone formation or resorption markers [869]

A clinical trial of once-weekly TZT in T2DM patients illustrated that at 26 weeks of treatment, TZT led to the significant reduction of intercellular adhesion molecule 1 (ICAM-1), growth differentiation factor 15 (GDF-15), chitosan-3 like protein 1 (YKL-40), leptin and CRP compared to the baseline values

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