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As underlying mechanisms, it has been reported that GLP-1 causes renal vasodilatation, increases renal blood flow, increases glomerular filtration rate, inhibits the Na + /H + exchanger 3 in proximal tubule and decreases sodium, bicarbonate and water reabsorption [12, 14]

10.2174/1574886315999201208212356 63 JelsingJ.VrangN.HansenG.RaunK.Tang-ChristensenM.KnudsenL

5-HT containing enteroendocrine cells characterised by morphologies, patterns of hormone co-expression, and relationships with nerve fibres in the mouse gastrointestinal tract

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Lira (GLP-1R) can reduce the occurrence of hepatic steatosis in vivo and in vitro by enhancing autophagy and lipid degradation through the GLP-1R-transcription factor EB (TFEB)-mediated autophagy lysosomal pathway [37]