glp-1 review A Comprehensive of the Role of Agonists in Weight Management and Their Effect on Metabolic Parameters Such as Blood Glucose, Cholesterol, and Blood Pressure GLP-1 therapy appears to reduce

However, semaglutide has FDA-approved uses under specific brand names and indications, while retatrutide remains investigational

a Values represent pooled placebo-adjusted mean differences (95% confidence interval)

2020;8:e001706

Jonathan Terry, DO, QME, DABPN, ABIHM Osteopathic physician Assistant dean of community clinical education, California Health Sciences University College of Osteopathic Medicine Disclosures: Terry reports no relevant financial disclosures

Thyroid function changes Some studies and case reports suggest GLP-1s may lower thyroid stimulating hormone (TSH) levels, possibly through direct effects on the hypothalamic-pituitary-thyroid (HPA) axis, and delayed gastric emptying (affecting medication absorption)