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Both medications affect gastric motility and liver metabolism, which can alter alcohol tolerance

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11,12 The risk of complications in SUSTAIN-6 was highest among patients with pre-existing diabetic retinopathy and rapid HbA1c reduction, suggesting that the findings reflect the early worsening of diabetic retinopathy that can occur with any method of lowering glucose, rather than direct retinal toxicity from GLP-1 RAs

For example, other GLP-1 receptor agonists like liraglutide and exenatide have also been reported to cause similar skin issues