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Contrarily, genetic ablation of Sirt1 in the intestinal epithelium deteriorates age-associated intestinal inflammation and dysbiosis partly by modulating bile acid metabolism [101]

Tight muscles are more likely to cramp, especially during exercise or at night

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The exclusive expression of GCG in pancreatic -cells, enteroendocrine L cells, and some neurons in the brainstem underlines its pivotal role (57)
