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Signs of Severe Hair Loss and Next Steps Sudden heavy shedding Visible thinning Hair shedding lasting several months

Tiredness may result from reduced caloric intake, blood glucose changes, gastrointestinal symptoms, or the body's adjustment to metabolic shifts

Additionally, intracerebroventricular delivery of Ex-4 has been found to dose-dependently attenuate cue-evoked dopamine activity, further underscoring the direct influence of GLP-1R signaling on neural circuits governing reinforcement and motivation (Konanur et al., 2020)

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Both are administered as once-weekly injections and may help eligible patients reduce appetite, improve portion control, and support meaningful weight loss when combined with nutrition and lifestyle changes