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For self-insured employers (who bear the direct cost of pharmacy claims), adding Wegovy to the formulary without restrictions increases annual per-employee costs by $800 to $1,600 based on uptake rates (AMCP, 2025)

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During active weight loss, appetite may decrease, motivation may be high, and progress may be visible

This mechanism triggers several physiological changes that can impact reproductive hormones

Amylin therapies Some drugs currently in development take a different approach, targeting receptors for a different hormone: amylin, which is co-secreted, alongside insulin, by the pancreas to slow gastric emptying, suppress glucagon secretion and signal feelings of fullness