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Description
Discoveries of GIP and GLP-1 The first incretin, GIP, was purified from canine intestinal extracts in the late 1960s (8) and initially named gastric inhibitory polypeptide (9) because the peptide inhibited gastrin-stimulated H + secretion (10)

Sources Rhodes, R

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In particular, treatment effect size may differ among each combination and be affected by patient clinical situations and targeting outcomes