switching from retatrutide to tirzepatide Retatrutide vs. tirzepatide: how they're different Retatrutide vs Tirzepatide | FIRST

So that is where we land on this with the principles

Helmstdter J, Frenis K, Filippou K, Grill A, Dib M, Kalinovic S, Pawelke F, Kus K, Krller-Schn S, Oelze M, Chlopicki S, Schuppan D, Wenzel P, Ruf W, Drucker DJ, Mnzel T, Daiber A, Steven S

These findings support CagriSema as a first-line option for patients with obesity and/or type 2 diabetes, offering the greatest weight loss and cardiometabolic improvements alongside the most favorable GI tolerability profile

Changes in injection site response

70 In the STEP HFpEF trial, higher changes in KCCQ-CSS were linearly associated with weight loss with semaglutide (5.9-point increase in KCCQ-CSS per 10% body weight loss)