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The authors hypothesize that this paradoxical worsening is due to a cytokine imbalance, similar to what is seen with the exacerbation of disease after administration of biological treatments like anti-TNF, which increases interferon (IFN)- release and leukocyte chemotaxis [25]

Our team carefully considers any potential contraindications or medication interactions to ensure your safety

doi: 10.1136/bmjopen-2020-047993

patients should not foot the bill for global innovation. Still, he cautioned against importing foreign prices from other countries, and instead called on policymakers to target PBMs

But a growing number of formulators are starting to question whether precursor-only strategies are solving the entire problem