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These pleiotropic effects include the reduction of BW and BP, the improvement of lipid metabolism and a spectrum of cardioprotective effects
Yet the question of cost is an important one
Phentermine raises cardiovascular risk markers
The combination yields greater weight loss than either agent alone, with mean reductions in body weight of approximately 20.4% over 68 weeks in non-diabetic adults and 13.7% in those with type 2 diabetesfar exceeding placebo and monotherapy arms
Some of these drugs are now also approved to reduce the risk of heart attacks , strokes, and heart-related deaths in certain populations
