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Nature medicine, 25(7), 10961103

Conclusion Significant weight regain occurred 8 weeks after discontinuation of AOMs and was sustained through 20 weeks

For practitioners, this changes the way we think about intervention: Less guesswork More precision Better adherence driven by satiety Stronger, more predictable outcomes Science

Glucagon-like peptide 1 receptor agonists (GLP-1 RAs) are a class of agents that have evolved rapidly in recent years

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