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Notably, siRNA-mediated inhibition of both AMPK and SIRT6 reversed the GLP-1RA-induced suppression of SREBP-2 expression in PA-treated cells (Fig

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& Dubourg, J

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[DOI] [PubMed] [Google Scholar] Kim T

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Further, administration of exogenous ghrelin in food-sated individuals mimics the enhancement of brain BOLD response to food cues induced by fasting, whereas GLP-1R antagonism prevents the reduction of brain reactivity to food cues after consuming a meal

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