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New-generation 5-HT4 agonists have high selectivity for 5-HT4 receptors, with little affinity for other serotoninergic and other classes of receptors [53]

The NHS recommends 6-8 glasses of fluid daily, sipping regularly throughout the day rather than consuming large amounts at once

If youre high-risk (active GI symptoms, recent dose increase, known delayed emptying), your team may use a liquid diet the day prior, point-of-care gastric ultrasound, or a brief medication hold